I drove from Cairns to Adelaide in two weeks. Of course, you can do the same route just the other way around. You also can take more time. If you complete the same route, you will drive at least 5.000 km in two weeks, so I wouldn’t recommend to go for less than 14 days. Because otherwise it will be tough to drive your needed kilometers and still have some relaxed days with not so much driving and more sightseeing.
In the picture below you can see the main route which I did. I started in Cairns -> Undara Volcanic National Park -> Karumba -> Mount Isa -> Tennant Creek -> Alice Springs -> Kings Canyon -> Uluru & Kata Tjuta National Park -> Coober Pedy -> Port Augusta.
In this post, I will write about the two weeks itinerary in general and in following ones I will give more information about important places.